Ki-67

Quantitative Analysis of Ki67, a Prognostic Biomarker in Gastroenteropancreatic Neuroendocrine Tumors
Ki67 labeling index (LI) is the preferred method of establishing grade for gastroenteropancreatic neuroendocrine tumors (GEP-NETs). There are a number of acceptable methods for calculating the Ki67 LI in GEP-NETs, but application of quantitative image analysis is a promising method to increase accuracy and repeatability. KiNet is a single-stage deep-learning-based detection and classification pipeline for Ki67 LI with performance meeting or exceeding the current state of the art.
May 19, 2022 2:00 PM — 3:00 PM MD Anderson Cancer Center (Virtual)
Toby C. Cornish
Quantitative Analysis of Ki67, a Prognostic Biomarker in Gastroenteropancreatic Neuroendocrine Tumors
Generative Adversarial Domain Adaptation for Nucleus Quantification in Images of Tissue Immunohistochemically Stained for Ki-67.
PURPOSE: We focus on the problem of scarcity of annotated training data for nucleus recognition in Ki-67 immunohistochemistry …
Xuhong Zhang, Toby C. Cornish, Lin Yang, Tellen D. Bennett, Debashis Ghosh, Fuyong Xing
Cite DOI
Pixel-to-Pixel Learning With Weak Supervision for Single-Stage Nucleus Recognition in Ki67 Images
OBJECTIVE: Nucleus recognition is a critical yet challenging step in histopathology image analysis, for example, in Ki67 …
Fuyong Xing, Toby C. Cornish, Tell Bennett, Debashis Ghosh, Lin Yang
Cite DOI
A single institution's 26-year experience with nonfunctional pancreatic neuroendocrine tumors: a validation of current staging systems and a new prognostic nomogram.
OBJECTIVE: To validate the 2010 American Joint Committee on Cancer (AJCC) and 2006 European Neuroendocrine Tumor Society (ENETS) tumor …
Trevor A. Ellison, Christopher L. Wolfgang, Chanjuan Shi, John L. Cameron, Peter Murakami, Liew Jun Mun, Aatur D. Singhi, Toby C. Cornish, Kelly Olino, Zina Meriden, Michael Choti, Luis A. Diaz, Timothy M. Pawlik, Richard D. Schulick, Ralph H. Hruban, Barish H. Edil
Cite DOI
Grading of well-differentiated pancreatic neuroendocrine tumors is improved by the inclusion of both Ki67 proliferative index and mitotic rate.
The grading system for pancreatic neuroendocrine tumors (PanNETs) adopted in 2010 by the World Health Organization (WHO) mandates the …
Chad M. McCall, Chanjuan Shi, Toby C. Cornish, David S. Klimstra, Laura H. Tang, Olca Basturk, Liew Jun Mun, Trevor A. Ellison, Christopher L. Wolfgang, Michael A. Choti, Richard D. Schulick, Barish H. Edil, Ralph H. Hruban
Cite DOI
Software-automated counting of Ki-67 proliferation index correlates with pathologic grade and disease progression of follicular lymphomas
OBJECTIVES: To examine the accuracy of software-assisted measurement of the Ki-67 proliferation index (PI) and its correlation with the …
Mark A. Samols, Nathan E. Smith, Jonathan M. Gerber, Milena Vuica-Ross, Christopher D. Gocke, Kathleen H. Burns, Michael J. Borowitz, Toby C. Cornish, Amy S. Duffield
Cite DOI