Genetic

Genome-wide characterization of human L1 antisense promoter-driven transcripts
BACKGROUND: Long INterspersed Element-1 (LINE-1 or L1) is the only autonomously active, transposable element in the human genome. L1 …
Steven W. Criscione, Nicholas Theodosakis, Goran Micevic, Toby C. Cornish, Kathleen H. Burns, Nicola Neretti, Nemanja Rodic
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DNA hypomethylation arises later in prostate cancer progression than CpG island hypermethylation and contributes to metastatic tumor heterogeneity
Hypomethylation of CpG dinucleotides in genomic DNA was one of the first somatic epigenetic alterations discovered in human cancers. …
Srinivasan Yegnasubramanian, Michael C. Haffner, Yonggang Zhang, Bora Gurel, Toby C. Cornish, Zhijin Wu, Rafael A. Irizarry, James Morgan, Jessica Hicks, Theodore L. DeWeese, William B. Isaacs, G. Steven Bova, Angelo M. De Marzo, William G. Nelson
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Globular domains of agrin are functional units that collaborate to induce acetylcholine receptor clustering
Agrin, an extracellular matrix protein involved in neuromuscular junction formation, directs clustering of postsynaptic molecules, …
Toby C. Cornish, Jamin Chi, Steve Johnson, Yang Lu, James T. Campanelli
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